Daniel Griffin provides a clinical report on COVID-19, then we discuss decline of virus-specific bone marrow B cells within a year after influenza vaccination, the push to release SARS-CoV-2 vaccines before completion of phase 3 trials, and absence of evidence for infectious virus in aerosols. Click arrow to playDownload TWiV 660 ...

Christian Drosten returns to TWiV to provide an update on the COVID-19 situation in Germany, and general thoughts on testing, immunity, vaccines, therapeutics, epidemiology, reopening schools, and what will happen this fall. Click arrow to playDownload TWiV 659 (72 MB .mp3, 120 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

by Gertrud U. Rey There are currently 315 therapeutic drugs and 210 vaccine candidates in development to treat or prevent SARS-CoV-2 infection. Many of these vaccines are designed to be administered by injection into the muscle.  Intramuscular injection of a vaccine antigen typically induces a systemic (serum) immune response that involves the ...

Daniel Griffin provides a clinical report on COVID-19, then we discuss CDC softening testing guidelines, Moderna vaccine phase I results in older people, Abbott's $5 rapid antigen test, and reinfection with a distinct SARS-CoV-2 isolate, followed by listener email. Click arrow to playDownload TWiV 658 (85 MB .mp3, 141 min)Subscribe (free): iTunes, Google ...

Not only the popular press but even some of my distinguished science colleagues are claiming that the recent report of reinfection of a COVID-19 patient is the end of the world. Nothing could be farther from the truth. First, the facts. The patient is a healthy Hong Kong male who ...