Virology

Offit on vaccines and autism

If you are not convinced that vaccines are safe, please listen to a conversation between Dr. Ginger Campbell of the Brain Science Podcast and Dr. Paul Offit. Dr. Offit is a pediatrician who is also Chief of Infectious Diseases and Director of Vaccine Education at the University of Pennsylvania School ...

Origin of current influenza H1N1 virus

Influenza viruses of two subtypes, H1N1 and H3N2, have been causing respiratory infections in humans since 1977. Before that year, it was believed that only one human subtype circulated each flu season. How did this unusual situation come about? Major changes in the surface glycoproteins of influenza virus - called ...

TWiV #22: Viral Bioinformatics

In episode #22 of This Week in Virology, Vincent and Chris Upton converse about hepatitis B in India, AIDS gene therapy with a ribozyme, antibodies that neutralize many influenza virus strains, killing tumors with vaccinia virus, myxoma virus of rabbits, and the Viral Bioinformatics Resource Center. Click the arrow above ...

A plethora of papillomaviruses

When Harald zur Hausen identified the first human papillomavirus (HPV-16) in 1983 in women with cervical cancer, little did he know he would receive the Nobel Prize in Medicine for this discovery 25 years later. He probably also did not know how difficult it would be to propagate these viruses in ...

Dreaming of inactivated poliovirus vaccine

The World Health Organization's global polio eradication effort uses the live, attenuated poliovirus vaccines developed by Albert Sabin. When the eradication program was announced in 1988, the goal was to eliminate global poliomyelitis, then cease immunization with poliovirus at some point in the future. In 2002 an outbreak of polio ...
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