Virology
Pathogenesis of influenza in humans
By Vincent Racaniello
When influenza virus is introduced into the respiratory tract, by aerosol or by contact with saliva or other respiratory secretions from an infected individual, it attaches to and replicates in epithelial cells. The virus replicates in cells of both the upper and lower respiratory tract. Viral replication combined with the ...
Futures in Biotech 43: Temporal Alien Mammoth Overlords
By Vincent Racaniello
I joined host Marc Pelletier and Andre Nantel, Justin Sanchez, and Dave Brodbeck for a discussion on recent big stories in bioscience. Topics included wooly mammoths, cybernetics, viruses in the oceans, and controlling your computer with your brain. Download Futures in Biotech 43 or subscribe to the podcast in iTunes.
TWiV 34: Arsenic and facemasks
By Vincent Racaniello
On episode 34 of the podcast "This Week in Virology", Vincent, Alan, and Stephen Morse discuss progressive vaccinia in a smallpox vaccinee, arsenic and influenza in mice, facemasks and flu transmission, and antigenic and genetic analyses of the new H1N1 influenza virus. [powerpress url="http://traffic.libsyn.com/twiv/TWiV034.mp3"] Click the arrow above to play, ...
Lujo virus, a new hemorrhagic fever virus from Southern Africa
By Vincent Racaniello
A new member of the arenavirus family, Lujo virus, has been identified in patients who died during an outbreak of hemorrhagic fever in late 2008. Sequence analysis reveals that Lujo is a new arenavirus, genetically distinct from other members of the family which includes Lassa virus. A patient with unexplained ...
Influenza microneutralization assay
By Vincent Racaniello
The microneutralization assay is another technique used by the Centers for Disease Control and Prevention to determine that some adults have serum cross-reactive antibodies to the new influenza H1N1 virus. Let's explore how this assay works. Viral replication is often studied in the laboratory by infecting cells that are grown ...