Virology
TWiV 35: Much achoo about nothing
By Vincent Racaniello
In episode 35 of the podcast "This Week in Virology", Vincent, Alan, Dick, and Richard Kessin talk about Lujo virus, a new arenavirus, influenza, WHO rewriting pandemic rules, adjuvants, and a brief history of microbiology. [powerpress url="http://traffic.libsyn.com/twiv/TWiV035.mp3"] Click the arrow above to play, or right-click to download TWiV #35 or ...
Interferons and secondary pneumonia after influenza
By Vincent Racaniello
Now that we have discussed influenza pathogenesis in humans and the innate immune defenses, we can tackle the conclusion that type I IFN mediates the development of secondary bacterial pneumonia in mice. Secondary bacterial pneumonia occurs after the patient has begun to recover from influenza infection, and often influenza virus ...
How influenza virus inhibits early antiviral responses
By Vincent Racaniello
The fact that viruses routinely and frequently cause disease shows that our defense mechanisms are imperfect. This occurs in large part because nearly every viral genome encodes one or more countermeasures to modulate host defenses. Influenza virus is no exception. One of the viral proteins, called NS1, is particularly adept ...
Innate immune defenses
By Vincent Racaniello
In response to viral infection, many organisms mount a remarkable defense known as the immune response. This response to viral infection consists of an innate, or nonspecific component, and an adaptive, or specific defense. The innate response is considered the first line of immune defense because it is active even ...
Virology pop quiz
By Vincent Racaniello
The following is from a story posted 2 June 2009 in Central Florida News 13: OCOEE -- Grief counselors will be available at Ocoee High School Tuesday after a student died suddenly from an unidentified virus Sunday. Here are my questions. 1. How can it be stated that the student died 'from ...