This Week in Virology listener Raphael D. Fernandez, M.D. has kindly transcribed my conversation with Dr. Peter Palese that was aired on the podcast on 6 May 2009. You can download the transcript from the show notes page. Many thanks to Dr. Fernandez for the transcript!

In episode 35 of the podcast "This Week in Virology", Vincent, Alan, Dick, and Richard Kessin talk about Lujo virus, a new arenavirus, influenza, WHO rewriting pandemic rules, adjuvants, and a brief history of microbiology. [powerpress url="http://traffic.libsyn.com/twiv/TWiV035.mp3"] Click the arrow above to play, or right-click to download TWiV #35 or ...

Now that we have discussed influenza pathogenesis in humans and the innate immune defenses, we can tackle the conclusion that type I IFN mediates the development of secondary bacterial pneumonia in mice. Secondary bacterial pneumonia occurs after the patient has begun to recover from influenza infection, and often influenza virus ...

The fact that viruses routinely and frequently cause disease shows that our defense mechanisms are imperfect. This occurs in large part because nearly every viral genome encodes one or more countermeasures to modulate host defenses. Influenza virus is no exception. One of the viral proteins, called NS1, is particularly adept ...

In response to viral infection, many organisms mount a remarkable defense known as the immune response. This response to viral infection consists of an innate, or nonspecific component, and an adaptive, or specific defense. The innate response is considered the first line of immune defense because it is active even ...