Virology
Virus neutralization by antibodies
By Vincent Racaniello
The antibody response is crucial for preventing many viral infections and may also contribute to resolution of infection. When a vertebrate is infected with a virus, antibodies are produced against many epitopes on multiple virus proteins. A subset of these antibodies can block virus infection by a process that is called neutralization. ...
Adaptive immune defenses: Antibodies
By Vincent Racaniello
With the looming prospect of mass immunization against influenza, it's important to understand how vaccines work. To do this we must have a good understanding of adaptive immune defenses. Today we'll begin a discussion of the humoral arm of the adaptive immune response - antibodies. Antibodies are large proteins produced ...
Name a scientist results
By Vincent Racaniello
While most adults cannot name a scientist, the readers of virology blog can identify many of them. I asked readers to spontaneously name just one scientist, and I received 204 responses. Nine of the individuals named were not scientists; that left 195 responses out of 204, indicating that 96% of ...
TWiV 41: Fish flu
By Vincent Racaniello
Hosts: Vincent Racaniello, Dick Despommier, Alan Dove, and Rich Condit On episode #41 of the podcast "This Week in Virology", Vincent, Dick, Alan and Rich Condit chat about infectious salmon anemia virus, virus-resistant grapevines, virulence of pandemic H1N1 influenza virus, origin of 1918 influenza virus, holy water ban to halt influenza, ...
Hand hygiene removes influenza virus
By Vincent Racaniello
Dispensers of alcohol-based rubs are appearing in public places in an attempt to reduce the spread of pandemic influenza. Are these effective at removing virus from hands? In a recent study, the hands of twenty vaccinated, antibody-positive volunteers were contaminated with 10,000,000 TCID50 of a 1999 seasonal H1N1 influenza virus ...
