Virology

Influenza PB1-F2 protein and viral fitness

The second RNA segment of the influenza virus genome encodes the PB1 protein - part of the viral RNA polymerase - and, in some strains, a second protein called PB1-F2. The latter protein is believed to be an important determinant of influenza virus virulence. The absence of a full-length PB1-F2 ...

No tetravalent influenza vaccine

Two different influenza vaccines will be available in the fall of 2009. One will be a trivalent preparation comprising seasonal influenza H3N2 and H1N1 strains, plus an influenza B virus strain. A monovalent vaccine will also be available against the 2009 pandemic H1N1 strain. Many readers of virology blog have ...

Transmission of influenza

In temperate climates, influenza displays distinct seasonality: infections mainly occur from November through March in the northern hemisphere, and from May to September in the southern hemisphere. The results of experiments in guinea pigs have revealed that aerosol transmission of influenza virus is most efficient in cold and dry conditions, ...

US President’s report on 2009 H1N1 influenza

President Obama's Council of Advisors on Science and Technology (PCAST) has released a report assessing H1N1 preparations. According to the White House Office of the Press Secretary: A Presidential advisory group of the nation's leading scientists and engineers today released a new report assessing the Obama Administration's preparations for this ...

TWiV 46: Virus entry into cells

Hosts: Vincent Racaniello and Dick Despommier In episode #46 of the podcast "This Week in Virology", Vincent and Dick continue virology 101 with a discussion of virus entry into cells, then answer reader email on colony collapse disorder and viruses that confer a benefit to their host. [powerpress url="http://traffic.libsyn.com/twiv/TWiV046.mp3"] Click ...
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