Virology
TWiP 2: General parasitism
By Vincent Racaniello
Hosts: Vincent Racaniello and Dickson Despommier On episode 2 of the podcast "This Week in Parasitism", Vincent and Dick classify parasites according to whether or not they are transmitted by a vector, then consider the implications of long-lived parasites. [powerpress url="http://traffic.libsyn.com/twip/TWiP002.mp3"] Click the arrow above to play, or right-click to ...
Rhinovirus and zinc part 3
By Vincent Racaniello
So far in my experiments to understand inhibition of rhinovirus replication by ZnCl2 I've found that at a concentration of 0.1 mM, viral plaque formation is inhibited but not sufficiently to be able to select resistant mutants. Attempts to use higher concentrations of the metal have consistently failed. When I ...
TWiV 60: Making viral RNA
By Vincent Racaniello
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dick continue Virology 101 with a discussion of how RNA viruses produce mRNA and replicate their genomes. [powerpress url="http://traffic.libsyn.com/twiv/TWiV060.mp3"] Click the arrow above to play, or right-click to download TWiV #60 (51 MB .mp3, 71 minutes) Subscribe to TWiV in iTunes, by ...
Virology lectures
By Vincent Racaniello
Each year I teach basic virology to medical, dental, and nursing students here at Columbia University Medical Center. You can find all the lecture videos, slides, and readings here at virology blog: virology.ws/course.
Clinical benefit of lentiviral gene therapy in two patients with a rare neurologic disease
By Vincent Racaniello
X-linked adrenoleukodystrophy (ALD) is a rare neurologic disease caused by a defect in a gene required for normal ABCD1 transporter function. The lack of this function leads to progressive demyelination, severe neurologic disease and death in males, often in childhood. ALD disease progression can be controlled by allogeneic hematopoietic cell ...
