Virology
Second H1N1 peak in US
By Vincent Racaniello
As week 46 of 2009 comes to a close, the Centers for Disease Control and Prevention reports that influenza has peaked in the US. That conclusion is based on the agency's influenza surveillance program, summarized in this figure: Does this mean that pandemic influenza is over? Absolutely not. This is ...
Raltegravir inhibits murine leukemia virus: implications for chronic fatigue syndrome?
By Vincent Racaniello
The finding that a retrovirus, XMRV, is associated with chronic fatigue syndrome has lead to the suggestion that the disease might be treated with some of the antiviral drugs used to treat AIDS. The integrase inhibitor Raltegravir has been found to block the replication of murine leukemia virus, which is ...
Safety of influenza 2009 H1N1 vaccine
By Vincent Racaniello
A number of readers have asked when we would have information about the safety of the influenza 2009 H1N1 vaccine. The World Health Organization has just released briefing note #16 "Safety of pandemic vaccines" in which they summarize vaccination information from 16 countries in which 80 million doses of vaccine ...
Poliovirus on BBC radio
By Vincent Racaniello
At the end of 1981, the year that I had shown that cloned poliovirus DNA is infectious, BBC Radio asked me to do an interview about the work. The name of the show was Science Now but I can't recall who was the host. Whoever he was, he didn't understand ...
Novartis influenza A H1N1 vaccine clinical data
By Vincent Racaniello
Although the influenza 2009 H1N1 vaccine produced by Novartis, Fluvirin, was previously approved for use in the US, the clinical data supporting its safety and immunogenicity had not been released. The company has now issued a media release containing interim clinical data on the effects of the vaccine in humans. ...