Virology
Are the bees vanishing?
By Vincent Racaniello
There is some evidence that viruses are involved in colony collapse disorder, a phenomenon in which worker bees disappear. This condition is receiving a great deal of attention ranging from basic scientific research (summarized on TWiV 46) to a PBS episode to a documentary entitled Colony which says that "The ...
TWiV 62: Persistence of West Nile virus
By Vincent Racaniello
Hosts: Vincent Racaniello, Dickson Despommier, and Alan Dove On episode #62 of the podcast This Week in Virology, Vincent, Dickson, and Alan discuss STEP HIV-1 vaccine failure caused by the adenovirus vector, presence of West Nile virus in kidneys for years after initial infection, adaptation of the influenza viral RNA ...
Rhinovirus and zinc part 4: cell toxicity
By Vincent Racaniello
My experiments to understand how ZnCl2 inhibits rhinovirus replication have been thwarted by the finding that concentrations of the salt higher than 0.1 mM are toxic for cultured HeLa cells. The cells can tolerate 0.1 mM but not 0.2 mM ZnCl2. Last week I asked whether I could identify a ...
Influenza virus growth in eggs
By Vincent Racaniello
Before the development of cell culture, many viruses were propagated in embryonated chicken eggs. Today this method is most commonly used for growth of influenza virus. The excellent yield of virus from chicken eggs has led to their widespread use in research laboratories and for vaccine production. In fact the ...
Futures in Biotech 50: More biotech stories
By Vincent Racaniello
I joined host Marc Pelletier and George Farr, Justin Sanchez, and Dave Brodbeck for a discussion on recent big stories in bioscience. Topics included erasing memory, controlling neurons with light, the role of the new virus XMRV in prostate cancer and chronic fatigue syndrome, and prions as genetic elements in ...
