If you have been following the results of my experiments on inhibition of rhinovirus replication by ZnCl2, you know that I've been trying to determine why concentrations of the salt higher than 0.1 mM are toxic to HeLa cells. I have found that 0.1 mM ZnCl2 does inhibit rhinovirus plaque ...

There is some evidence that viruses are involved in colony collapse disorder, a phenomenon in which worker bees disappear. This condition is receiving a great deal of attention ranging from basic scientific research (summarized on TWiV 46) to a PBS episode to a documentary entitled Colony which says that "The ...

Hosts: Vincent Racaniello, Dickson Despommier, and Alan Dove On episode #62 of the podcast This Week in Virology, Vincent, Dickson, and Alan discuss STEP HIV-1 vaccine failure caused by the adenovirus vector, presence of West Nile virus in kidneys for years after initial infection, adaptation of the influenza viral RNA ...

My experiments to understand how ZnCl2 inhibits rhinovirus replication have been thwarted by the finding that concentrations of the salt higher than 0.1 mM are toxic for cultured HeLa cells. The cells can tolerate 0.1 mM but not 0.2 mM ZnCl2. Last week I asked whether I could identify a ...

Before the development of cell culture, many viruses were propagated in embryonated chicken eggs. Today this method is most commonly used for growth of influenza virus. The excellent yield of virus from chicken eggs has led to their widespread use in research laboratories and for vaccine production. In fact the ...