Yesterday I terminated the last remaining mice in my small colony, including the line of poliovirus receptor transgenic mice that we established here in 1990. Remarkably, I had never written about this animal model for poliomyelitis which has played an important role in the work done in my laboratory. While ...

Hosts: Vincent Racaniello, Rich Condit, Dickson Despommier, Alan Dove, and Matt Evans Matt Evans joins Vincent, Rich, Dickson, and Alan to deconstruct a mouse model for hepatitis C virus infection. [powerpress url="http://traffic.libsyn.com/twiv/TWiV141.mp3"] Click the arrow above to play, or right-click to download TWiV #141 (117 MB .mp3, 97 minutes). Subscribe to TWiV ...

This article was written for extra credit by a student in my recently concluded virology course. by Adriana Lopez The expression Happy as a Clam€ comes with new meaning as hepatitis A virus has been detected in clams, mussels, and oysters in markets for human consumption. As bivalve shellfish are excellent ...

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Judy Lieberman Vincent, Alan, Rich, and Judy Lieberman review the use of CD4 aptamer-siRNA chimeras to inhibit HIV transmission. [powerpress url="http://traffic.libsyn.com/twiv/TWiV140.mp3"] Click the arrow above to play, or right-click to download TWiV #140 (110 MB .mp3, 92 minutes). Subscribe to TWiV (free) ...

Analysis of poliovirus recovered from the stool of a patient with fatal poliomyelitis revealed that she had been infected with the virus 12 years earlier, probably when one of her children received the oral poliovirus vaccine. This case has the longest known incubation period for vaccine-derived poliomyelitis, and highlights our ...