In COVID-19 clinical update #96, Daniel Griffin reviews Omicron in South Africa, rapid antigen tests, viral coinfections, isolation and quarantine, saliva preferred for Omicron, risk factors for severe disease in vaccinated, Paxlovid dosing, and long COVID. Click arrow to playDownload TWiV 850 (58 MB .mp3, 48 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! ...

by Gertrud U. Rey Viruses that require access to the host cell nucleus typically get there by exploiting cellular motor proteins for their own transportation purposes. For example, herpesviruses use two cellular proteins called dynein and kinesin to shuttle their cargo to and from the nucleus. However, the exact mechanism ...

TWiV explores the impact of the intestinal virome on seroconversion after rotavirus vaccination, and implications of the ability of the SARS-CoV-2 beta variant to infect wild-type laboratory mice. Click arrow to playDownload TWiV 846 (61 MB .mp3, 102 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

In COVID-19 clinical update #94, Daniel Griffin reviews the FDA EUA for Paxlovid, test to stay in school, immunity after infection, variants and therapeutics, quarantine and isolation guidelines, Molnupiravir in non-hospitalized patients, and convalescent serum in outpatients. Hosts: Daniel Griffin and Vincent Racaniello Click arrow to playDownload TWiV 845 (58 MB .mp3, ...

Viruses of bacteria (bacteriophages or phages) have been engaged in a battle with their bacterial hosts for hundreds of millions of years. This conflict has driven the evolution of multiple bacterial defenses against phages, such as CRISPR-CAS and restriction/modification systems. But phages have also been engaged with other phages: apparently ...