Viruses of bacteria (bacteriophages or phages) have been engaged in a battle with their bacterial hosts for hundreds of millions of years. This conflict has driven the evolution of multiple bacterial defenses against phages, such as CRISPR-CAS and restriction/modification systems. But phages have also been engaged with other phages: apparently ...

TWiV provides an update on immunity to Omicron, results of a randomized controlled trial of face masks, and a study of correlates of protection against respiratory syncytial virus infection in the upper and lower respiratory tract of nonhuman primates. Click arrow to playDownload TWiV 841 (63 MB .mp3, 105 min)Subscribe (free): iTunes, Google Podcasts, RSS, email ...

In COVID-19 clinical update #92, Dr. Griffin reviews emerging data on the Omicron variant, much information about monoclonal antibody treatment, including expansion of EUA for Lilly's cocktail, FDA EUA for pre-exposure prophylaxis, outcomes after treatment, and investigation of subcutaneous or intramuscular administration; effect of adding immunomodulatory agents to usual care ...

It will be some time before a substantial fraction of the human population is immunized to prevent COVID-19. In the meantime, widespread use of face masks can have an impact on disease, a conclusion suggested by results of a trial carried out in Bangladesh. WHO would not recommend the use ...

TWiV reviews the impact of vaccination on SARS-CoV-2, the latest information on Omicron, West Nile virus transmission by organ transplantation, and why a 16 week interval between doses of BNT162b2 vaccine is better than a shorter interval. Click arrow to playDownload TWiV 839 (64 MB .mp3, 107 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Show notes ...