Virology

Influenza A viruses in bats

It is well known that aquatic birds are a major reservoir of influenza A viruses, and that pandemic human influenza virus strains of the past century derive viral genes from this pool. The recent discovery of two new influenza A viruses in bats suggests that this species may constitute another ...

TWiV 258: Hedging our bats

On episode #258 of the science show This Week in Virology, Matt joins the TWiV team to discuss the discovery of a SARS-like coronavirus in bats that can infect human cells, and what is going on with MERS-coronavirus. You can find TWiV #258 at www.microbe.tv/twiv.

The neuraminidase of influenza virus

The influenza virus particle is made up of the viral RNA genome wrapped in a lipid membrane (illustrated). The membrane, or envelope, contains three different kinds of viral proteins. The hemagglutinin molecule (HA, blue) attaches to cell receptors and initiates the process of virus entry into cells. I have written ...

TWiV 257: Caveat mTOR

On episode #257 of the science show This Week in Virology, the TWiV team consider how the kinase mTOR modulates the antibody response to provide broad protection against influenza virus, and explore the problems with scientific research. You can find TWiV #257 at www.microbe.tv/twiv.

John Holland, 83

John Holland, 1995 Virologist John Holland passed away on 11 October 2013. I asked former members of his laboratory for their thoughts on his career and what he meant to them. Bert Semler For more than 35 years, John Holland was a major figure and leading contributor in the study ...
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