Virology
Virology question of the week: What matters more, multiplicity of infection or virus concentration?
By Vincent Racaniello
This week's question comes from a graduate student studying virology, who writes: My professor recently said that really, the MOI doesn't matter in a culture, it is the concentration of viral particles in the media that matters. Ie: if you have 10 million cells or one cell, but you are ...
TWiV 283: No Reston for the weary
By Vincent Racaniello
On episode #283 of the science show This Week in Virology, Jens Kuhn speaks with the TWiV team about filoviruses, including the recent Ebola virus outbreak in Guinea. You can find TWiV #283 at www.microbe.tv/twiv.
Unusual mortality pattern of 1918 influenza A virus
By Vincent Racaniello
The 1918 influenza pandemic was particularly lethal, not only for the very young and the very old (as observed for typical influenza), but unexpectedly also for young adults, 20 to 40 years of age (pictured). It has been suggested that the increased lethality in young adults occurred because they lacked protective ...
TWiV 282: Tamiflu and tenure too
By Vincent Racaniello
On episode #282 of the science show This Week in Virology, the TWiV team reviews a meta-analysis of clinical trial reports on using Tamiflu for influenza, and suggestions on how to rescue US biomedical research from its systemic flaws. You can find TWiV #282 at www.microbe.tv/twiv.
Virology question of the week: why a segmented viral genome?
By Vincent Racaniello
This week's virology question comes from Eric, who writes: I'm working on an MPH and in one of my classes we are currently studying the influenza virus. I'd forgotten that the genome is in 8 separate parts. Curious, I've been searching but can't find any information as to why that ...
