Virology
Unraveling the NEIDL
By Vincent Racaniello
The NEIDL (National Emerging Infectious Diseases Laboratory) at Boston University is a newly constructed biosafety level 4 facility which can be used to study the most dangerous human pathogens. The facility is amazingly safe, as we documented in our film about the facility, Threading the NEIDL. Some members of the ...
Virology question of the week
By Vincent Racaniello
On the science show This Week in Virology we receive many questions and comments, which are read every week. I also get many questions here on virology blog, which I tend to answer by email. However I think that everyone could benefit from these questions, so I've decided to post ...
TWiV 279: The missing LNC
By Vincent Racaniello
On episode #279 of the science show This Week in Virology, Vincent, Alan, and Kathy reveal how a retrovirus in the human genome keeps embryonic stem cells in a pluripotent state, from where they can differentiate into all cells of the body. You can find TWiV #279 at www.microbe.tv/twiv.
Retroviruses R us
By Vincent Racaniello
About eight percent of human DNA is viral - remnants of ancestral infections with retroviruses. These endogenous retroviral sequences do not produce infectious viruses, and most are considered to be junk DNA. But some of them provide important functions. The protein called syncytin, which is essential for formation of the ...
TWiV 278: Flushing HIV down the zinc
By Vincent Racaniello
On episode #278 of the science show This Week in Virology, Vincent, Dickson, Alan, and Kathy discuss disruption of the ccr5 gene in lymphocytes of patients infected with HIV-1. You can find TWiV #278 at www.microbe.tv/twiv.