Virology

TWiV 878: Shape matters sometimes

TWiV revisits chronic wasting disease of cervids and the ability of the prions to infect meadow voles and raccoons, and the suggestion that stochastic assembly of influenza virus particles may play a role in phenotypic diversity. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Amy Rosenfeld Click arrow to playDownload TWiV 878 ...

TWiV 877: COVID-19 clinical update #106 with Dr. Daniel Griffin

In COVID-19 clinical update #106, Daniel Griffin covers failure of ivermectin to improve hospitalization, increased hospitalization of children with Omicron, seroconversion of children versus adults, effectiveness of Pfizer mRNA vaccine in children, high vaccine effectiveness in Finland against Omicron, distinct long COVID clinical phenotypes, and estimating worldwide excess mortality. Click ...

Capsids and nucleocapsids

One aspect of virology that is confusing to students is the concepts of capsids and nucleocapsids. These two terms describe two different ways that viral nucleic acids and proteins are arranged in virus particles. The capsid (from the Latin capsa for box) is the protein shell surrounding the nucleic acid ...

TWiV 876: Spillover market with Michael Worobey

Michael Worobey joins TWiV to explain evidence that SARS-CoV-2 emerged via the wildlife trade and that the Huanan market was the unambiguous epicenter of the COVID-19 pandemic. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Guest: Michael Worobey Click arrow to playDownload TWiV 876 (128 MB .mp3, 107 min)Subscribe (free): Apple ...

TWiV 875: Animal house

TWiV discusses the virome of game animals in China, and the finding that binding of sarbecoviruses to ACE2 is an ancestral and evolvable trait. Hosts: Vincent Racaniello, Dickson Despommier, and Amy Rosenfeld Click arrow to playDownload TWiV 875 (128 MB .mp3, 107 min)Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
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