Virology
New Yorkers like their science from scientists
By Vincent Racaniello
I cannot pass up the opportunity to point out this wonderful quote by Ginia Ballafante in her NY Times piece, Fear of Vaccines Goes Viral. The article starts by noting an article on plummeting vaccination rates in Los Angeles: The piece had the virtue of offering New Yorkers yet another opportunity ...
TWiV 306: This Week in Ebolavirus
By Vincent Racaniello
On episode #306 of the science show This Week in Virology, the Grand Masters of the TWiV discuss Ebola virus transmission, air travel from West Africa, Ebola virus infectivity on surfaces, the Dallas Ebola virus patient, and Ebola virus in dogs. You can find TWiV #306 at www.microbe.tv/twiv.
Treatment of Ebola virus infection with brincidofovir
By Vincent Racaniello
The Liberian man who was diagnosed with Ebola virus infection after traveling to Dallas, Texas, was treated with an antiviral drug called brincidofovir. This drug had originally been developed to treat infections with DNA-containing viruses. Why was it used to treat an Ebola virus infection? Brincidofovir (illustrated) is a modified ...
Oral polio vaccine-associated paralysis in a child despite previous immunization with inactivated virus
By Vincent Racaniello
Poliovirus by Jason Roberts Vaccine-associated poliomyelitis caused by the oral poliovirus vaccine is rare, but its occurrence in a healthy, immunocompetent 6-month old child was highly unusual because the child had been previously immunized with two doses of the injected, inactivated poliovirus vaccine (IPV). The three poliovirus vaccine strains developed by Albert ...
The incubation period of a viral infection
By Vincent Racaniello
The time before the symptoms of a viral infection appear is called the incubation period. During this time, viral genomes are replicating and the host is responding, producing cytokines such as interferon that can have global effects, leading to the classical symptoms of an acute infection (e.g., fever, malaise, aches, pains, and nausea). ...
