Virology
Your viral past
By Vincent Racaniello
Did you ever wonder what different virus infections you have had in your lifetime? Now you can find out with just a drop of your blood and about $25. Immune defense systems of many hosts produce antibodies in response to virus infections. These large proteins, which are generally virus specific, can block ...
TWiV 339: Herpes and the sashimi plot
By Vincent Racaniello
On episode #339 of the science show This Week in Virology, tre TWiV amici present three snippets and a side of sashimi: how herpesvirus inhibits host cell gene expression by disrupting transcription termination. You can find TWiV #339 at www.microbe.tv/twiv.
Viruses in the extreme
By Vincent Racaniello
Many microbes live in extreme environments, encountering conditions that are very hot, very cold, highly acidic, or very salty. The viruses that infect such microbes must also be able to retain infectivity in extreme conditions. How do they do it? Clues come from the observations that the genomes of viruses ...
Sushi protects mosquitoes from lethal virus infections
By Vincent Racaniello
As far as I know, mosquitoes do not eat sushi. But mosquito cells have proteins with sushi repeat domains, and these proteins protect the brain from lethal virus infections. Mosquitoes are vectors for the transmission of many human viral diseases, including yellow fever, West Nile disease, Japanese encephalitis, and dengue hemorrhagic fever. Many ...
TWiV 337: Steamer
By Vincent Racaniello
On episode #337 of the science show This Week in Virology, Vincent meets up with Michael and Steve to discuss their finding of a transmissible tumor in soft-shell clams associated with a retrovirus-like element in the clam genome. You can find TWiV #337 at www.microbe.tv/twiv.