Virology
Permissive vaccines and viral virulence
By Vincent Racaniello
A permissive vaccine prevents disease in the immunized host, but does not block virus infection. Would a permissive vaccine lead to the emergence of more virulent viruses? This hypothesis is based on the notion that viruses which kill their hosts too quickly are not efficiently transmitted, and are therefore removed ...
Principles of Virology, Fourth Edition
By Vincent Racaniello
I am pleased to announce the publication by ASM Press of the fourth edition of our virology textbook, Principles of Virology. Two years in the making, this new edition is fully updated to represent the rapidly changing field of virology. Principles of Virology has been written according to the authors' philosophy that the ...
TWiV 347: Rose rosette and squirrel roulette
By Vincent Racaniello
On episode #347 of the science show This Week in Virology, Vincent, Alan, and Rich discuss the virus behind rose rosette disease, and fatal human encephalitis caused by a variegated squirrel bornavirus. You can find TWiV #347 at www.microbe.tv/twiv.
Transgenic pigs resistant to foot-and-mouth disease
By Vincent Racaniello
Image credit Foot-and-mouth disease virus (FMDV) infects cloven-hoofed animals such as cattle, pigs, sheep, goats, and many wild species. The disease caused by this virus is a substantial problem for farmers because infected animals cannot be sold. Transgenic pigs have now been produced which express a short interfering RNA (siRNA) and consequently ...
TWiV 346: A double helical career
By Vincent Racaniello
Episode #346 of the science show This Week in Virology was recorded at the 34th Annual Meeting of the American Society for Virology, where Vincent, Rich, and Kathy spoke with Joan Steitz, a tireless promoter of women in science and one of the greatest scientists of our generation. You can ...
