Virology
An Ebolavirus vaccine in Africa
By Vincent Racaniello
An Ebolavirus vaccine has shown promising results in a clinical trial in Guinea. This vaccine has been in development since 2004 and was made possible by advances in basic virology of the past 40 years. The ability to produce the Ebolavirus vaccine, called rVSV-EBOV, originates in the 1970s with the discovery of the enzyme ...
TWiV 348: Chicken shift
By Vincent Racaniello
On episode #348 of the science show This Week in Virology, Vincent and Rich discuss fruit fly viruses, one year without polio in Nigeria, and a permissive Marek's disease viral vaccine that allows transmission of virulent viruses. You can find TWiV #348 at www.microbe.tv/twiv.
Permissive vaccines and viral virulence
By Vincent Racaniello
A permissive vaccine prevents disease in the immunized host, but does not block virus infection. Would a permissive vaccine lead to the emergence of more virulent viruses? This hypothesis is based on the notion that viruses which kill their hosts too quickly are not efficiently transmitted, and are therefore removed ...
Principles of Virology, Fourth Edition
By Vincent Racaniello
I am pleased to announce the publication by ASM Press of the fourth edition of our virology textbook, Principles of Virology. Two years in the making, this new edition is fully updated to represent the rapidly changing field of virology. Principles of Virology has been written according to the authors' philosophy that the ...
TWiV 347: Rose rosette and squirrel roulette
By Vincent Racaniello
On episode #347 of the science show This Week in Virology, Vincent, Alan, and Rich discuss the virus behind rose rosette disease, and fatal human encephalitis caused by a variegated squirrel bornavirus. You can find TWiV #347 at www.microbe.tv/twiv.