Virology
Revisiting the PLoS One economics analysis of PACE
By Vincent Racaniello
On October 23rd, virology blog published the third installment of David Tuller's investigative report about the PACE study of treatments for ME/CFS. In the post, Dr. Tuller demonstrated that the key finding of an economic analysis of the PACE trial, published in PLoS One in 2012, was almost certainly false. ...
TWiV 368: Infected, you will be
By Vincent Racaniello
On episode #368 of the science show This Week in Virology, a plaque of virologists explores the biology of Zika virus and recent outbreaks, and the contribution of a filamentous bacteriophage to the development of biofilms. You can find TWiV #368 at www.microbe.tv/twiv.
Viruses help form biofilms
By Vincent Racaniello
Bacteria frequently grow in communities called biofilms, which are aggregates of cells and polymers. An example of a biofilm is the dental plaque on your teeth. Biofilms are medically important as they can allow bacteria to persist in host tissues and on catheters, and confer increased resistance to antibiotics and dessication. ...
A request for data from the PACE trial
By Vincent Racaniello
Mr. Paul Smallcombe Records & Information Compliance Manager Queen Mary University of London Mile End Road London E1 4NS Dear Mr Smallcombe: The PACE study of treatments for ME/CFS has been the source of much controversy since the first results were published in The Lancet in 2011. Patients have repeatedly raised objections ...
TWiEVO: This Week in Evolution
By Vincent Racaniello
To a molecular biologist, the word 'evolution' evokes images of fossils, dusty rocks, and phylogenetic trees covering eons. The fields of molecular biology and evolutionary biology diverged during the twentieth century, but new experimental technologies have lead to a fusion of the two disciplines. The result is that evolutionary biologists have the unprecedented ability to evaluate ...
