Virology
Antibodies to dengue virus enhance infection by Zika virus
By Vincent Racaniello
Model of Zika virus particle. E glycoprotein dimer is expanded at left. It has been speculated that the development of neurological disease and fetal abnormalities after Zika virus infection may be due to the presence of antibodies against other flaviruses that enhance disease. In support of this hypothesis, it has ...
Zika virus in Brazilian non-human primates
By Vincent Racaniello
Zika virus RNA has been detected in New World monkeys from the Northeast region of Brazil. This finding suggests that primates may serve as a reservoir host for the virus, as occurs in Africa. The results of numerous serological surveys have shown that different Old World monkeys in Africa and Asia, ...
TWiV 386: The dolphins did it
By Vincent Racaniello
Did you know that the evolution of ancient retroviruses, millions of years ago, can be traced by studying their genomes in the chromosomes of contemporary animals? Ted Diehl and Welkin Johnson join the TWiV team to tell us how they did it with mammals. All without a single wet experiment! ...
From trivalent to bivalent oral poliovirus vaccine
By Vincent Racaniello
For the first time since April of 1955, recipients of poliovirus vaccine will no longer receive all three serotypes. This past Sunday the World Health Organization orchestrated a synchronized switch from trivalent to bivalent oral poliovirus vaccine (OPV) in 150 countries. The reason for the switch is clear: type 2 poliovirus was declared ...
Interview with Thomas London
By Vincent Racaniello
A major new feature of the fourth edition of Principles of Virology is the inclusion of 26 video interviews with leading scientists who have made significant contributions to the field of virology. These in-depth interviews provide the background and thinking that went into the discoveries or observations connected to the concepts ...
