Virology
Animal viruses with separately packaged RNA segments
By Vincent Racaniello
There are many examples of viruses with segmented genomes - like influenza viruses - but these genomes segments are packaged in one virus particle. Sometimes the genome segments are separately packaged in virus particles. Such multicomponent viruses are commonly found to infect plants and fungi, but only recently have examples of ...
TWiV 403: It’s not easy being vaccine
By Vincent Racaniello
The TWiV team takes on an experimental plant-based poliovirus vaccine, contradictory findings on the efficacy of Flumist, waning protection conferred by Zostavax, and a new adjuvanted subunit zoster vaccine. You can find TWiV #403 at microbe.tv/twiv, or listen below. [powerpress url="http://traffic.libsyn.com/twiv/TWiV403.mp3"] Click arrow to play Download TWiV 403 (70 MB .mp3, 96 min) Subscribe (free): iTunes, RSS, email Become ...
Whole plant cells producing viral capsid protein as a poliovirus vaccine candidate
By Vincent Racaniello
Although the use of the live, attenuated (Sabin) poliovirus vaccines has been instrumental in nearly eradicating the virus from the planet, the rare reversion to virulence of these strains has lead to the World Health Organization to recommend their replacement with inactivated poliovirus vaccine (IPV). Unfortunately IPV is also not without ...
TWiV 402: The plight of the bumblebee
By Vincent Racaniello
Polio returns to Nigeria, Zika virus spreads in Miami, and virus infection of plants attracts bumblebees for pollination, from the virus gentlepeople at TWiV. You can find TWiV #400 at microbe.tv/twiv, or listen below. [powerpress url="http://traffic.libsyn.com/twiv/TWiV402.mp3"] Click arrow to play Download TWiV 402 (85 MB .mp3, 118 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!
Non-fatal attraction
By Vincent Racaniello
Volatile organic compounds that are emitted by plants - which play important roles in attracting insects - can be altered by virus infection. Infection by cucumber mosaic virus (CMV) increases the emissions that attract aphids, but the virus-altered plant juices are not so tasty, so the insect quickly leaves to spread virus ...
