Virology
Zika in the Guys
By Vincent Racaniello
In this episode of Virus Watch, we explore the finding that Zika virus infects the testis of mice, causing damage to the organ, reduced sperm production, and less fertility. The important question: does the same happen in humans? https://youtu.be/dQCuhSqsW7o
TWiV 414: Zika in the guys with Diamond
By Vincent Racaniello
On episode #414 of the science show This Week in Virology, Michael Diamond visits the TWiV studio to talk about chikungunya virus and his laboratory's work on a mouse model of Zika virus, including the recent finding of testicular damage caused by viral replication. You can find TWiV #414 at microbe.tv/twiv, or listen ...
Increased infectivity of Ebola virus glycoprotein from West Africa
By Vincent Racaniello
When viruses cross species, serial transmission may lead to the selection for mutations that confer improved replication or transmission in the new host. Identifying such mutations in human viruses is extremely difficult: we cannot conduct the appropriate experiments in humans, and often do not have viral isolates spanning the time from spillover through ...
TWiV 413: Partnerships not parachutes
By Vincent Racaniello
https://youtu.be/HqCByiOE4X8 From the EIDA2Z conference at Boston University, Vincent, Alan and Paul meet up with Ralph Baric, Felix Drexler, Marion Koopmans, and Stacey Schultz-Cherry to talk about discovering, understanding, protecting, and collaborating on emerging infectious diseases. You can find TWiV #413 at microbe.tv/twiv, or watch or listen here. [powerpress url="http://traffic.libsyn.com/twiv/TWiV413.mp3"] Click ...
Genome recombination across viral families
By Vincent Racaniello
A novel coronavirus isolated from bats in China is unusual because the genome contains a gene from a virus in a completely different family, the Reoviridae (link to paper). The finding suggests that recombination occurred between a (+) strand RNA virus and a virus with a segmented, double-stranded RNA genome. The ...
