The TWiV gurus describe how to use an orthogonal translation system to produce infectious but replication-incompetent influenza vaccines. You can find TWiV #420 at microbe.tv/twiv, or listen below. [powerpress url="http://traffic.libsyn.com/twiv/TWiV420.mp3"] Click arrow to play Download TWiV 420 (70 MB .mp3, 116 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!

In a recent editorial, the New York Times wrote about 'the breakdown of a shared public reality built upon widely accepted facts'. As a scientist, I am appalled by the disdain for facts shown by many in this country, including the President-Elect. Unfortunately, science is not without its share of fake information. The ...

The TWiVrific gang reveal how integration of a virophage into the nuclear genome of a marine protozoan enhances host survival after infection with a giant virus. You can find TWiV #419 at microbe.tv/twiv, or listen below. [powerpress url="http://traffic.libsyn.com/twiv/TWiV419.mp3"] Click arrow to play Download TWiV 419 (64 MB .mp3, 105 min) Subscribe (free): iTunes, RSS, email Become ...

Virophages (the name means virus eater) were first discovered to replicate only in amoeba infected with the giant mimiviruses or mamaviruses.  They reduce yields of the giant viruses, and also decrease killing of the host cell. Another virophage called mavirus has been found to integrate into the genome of its host and behaves like ...

The TWiVsters describe a new animal model for MERS coronavirus-induced acute respiratory distress syndrome, produced by CRISPR/Cas9 editing of the mouse gene encoding an ortholog of the virus receptor. You can find TWiV #418 at microbe.tv/twiv, or listen below. [powerpress url="http://traffic.libsyn.com/twiv/TWiV418.mp3"] Click arrow to play Download TWiV 418 (63 MB .mp3, 104 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!