Virology
Flu and the Y chromosome
By Vincent Racaniello
Disease and death caused by influenza virus are greater in human females than in males. But disease is more common in males from birth through age 15, after which more females are affected. In mice, genetic variation in the Y chromosome controls susceptibility to influenza virus infection (link to paper). ...
Trial By Error, Continued: CMRC to Virology Blog: F**k Off!
By Vincent Racaniello
by David Tuller, DrPH Well, not in those words, of course. It was all very polite. But that was the message. Here's what happened. On Monday, I posted an open letter to the members of the board of the CFS/ME Research Collaborative. The letter involved the false accusation of libel ...
Trial By Error, Continued: An Open Letter to the Board of the CFS/ME Research Collaborative
By Vincent Racaniello
by David Tuller, DrPH To Members of the Board of the CMRC: Not long ago, at the annual conference of the British Renal Society, your deputy chair disseminated the false accusation that I had libeled her. As a corollary to that, she also disseminated the false accusation that Dr. Racaniello, ...
TWiV 440: I hardly noumeavirus
By Vincent Racaniello
No problem not being nice to Dickson in this episode, because he's absent for a discussion of a new giant virus that replicates in the cytoplasm yet transiently accesses the nucleus to bootstrap infection. You can find TWiV #440 at microbe.tv/twiv, or listen below. Click arrow to play Download TWiV 440 (72 ...
A different kind of remote control
By Vincent Racaniello
Among the multitudes of eukaryotic viruses with DNA genomes, some replicate in the cell nucleus, while others avoid the nuclear bureaucracy and remain in the cytoplasm. But biology is not always so rigid: a new giant virus has been found that replicates in the cytoplasm, where it seems to recruit components ...
