Cindy, Steph, and Vincent reveal that lymphocyte trafficking through lymph nodes and lymph is circadian - it is dependent on the time of day. <span data-mce-type="bookmark" class="mce_SELRES_start"></span> Click arrow to play Download Immune 2 (53 MB .mp3, 87 min) Subscribe (free): iTunes, RSS, email Become a patron of Immune! Show notes at microbe.tv/immune

Amy Rosenfeld joins the TWiV team to talk about her career and her work on Zika virus neurotropism using embryonic mouse organotypic brain slice cultures. <span data-mce-type="bookmark" class="mce_SELRES_start"></span> Click arrow to play Download TWiV 468 (66 MB .mp3, 107 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

When you are infected with a microbe, pieces of the pathogen are picked up by sentinel dendritic cells and brought to local lymph nodes. There the sentinels present their gifts to lymphocytes - B (pictured; image credit) and T cells - who then decide if they are foreign, in which ...

Jon and Teddy Yewdell join the TWiV team to talk about their careers, their research, and the problems with biomedical research. Click arrow to play Download TWiV 467 (60 MB .mp3, 100 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv.

Written with Amy Rosenfeld, Ph.D. By infecting organotypic brain slice cultures from embryonic mice, we have shown that Zika virus has always been neurotropic. The same culture system provides information on how Zika virus infection of the developing brain might lead to microcephaly. The small heads observed in microcephalic children ...