Virology
Metabolic manipulations in virus-infected cells
By Vincent Racaniello
The large quantities of viral macromolecules and virus particles that are produced in an infected cell impose heavy demands on the host. Synthesis of the building blocks of a virus particle - nucleotides, amino acids, and sometimes fatty acids - requires energy, typically in the form of ATP. Synthesis of ...
TWiV 476: In ACOD1 we trust
By Vincent Racaniello
Nels joins the TWiV team to talk about his work on genomic accordions in vaccinia virus, hepatitis B virus in a 439 year old mummy, and viral induction of energy synthesis by a long noncoding RNA. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span><span data-mce-type="bookmark" style="display: inline-block; ...
A virus and a paradox in a 439 year old mummy
By Vincent Racaniello
Vesicopustular rash on face (C) and arm (D) of 439 year old mummy. Image credit. A study done in 1985 on a 16th century Italian mummy suggested that the two year old child had smallpox. Recent sequence analysis of tissues from the mummy now reveal the presence of hepatitis B ...
TWiV 475: Everything is viral
By Vincent Racaniello
In the first episode for 2018, the TWiV team reviews the amazing virology stories of 2017. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span> Click arrow to play Download TWiV 475 (67 MB .mp3, 110 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
TWiV 474: Call me fish meal
By Vincent Racaniello
The TWiVanguardians take on Bodo saltans virus, a leviathan which infects an abundant flagellated eukaryote in Earth's waters. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span><span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span>&lt;span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"&gt;&lt;/span&gt;&amp;lt;span data-mce-type="bookmark" ...