Virology
TWiV 492: CRISPR diagnostics
By Vincent Racaniello
The Masters of the TWiXome review the development of sensitive, portable, and field-based viral diagnostics using the CRISPR-Cas system. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span><span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span>&lt;span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"&gt;&lt;/span&gt;&amp;lt;span data-mce-type="bookmark" ...
Virus-proof cells?
By Vincent Racaniello
I am very skeptical about the pronouncement this week that a group of scientists plan to engineer cells to resist virus infection. The initiative is called Genome-Project-write (GP-write) and is composed of an international group of collaborators with the broader goal of designing and assembling a synthetic human genome. The ...
TWiV 491: The Ileum and the Odyssey
By Vincent Racaniello
The TWiVome deconstructs the evolutionary history of RNA viruses, and immune promotion of murine norovirus pathogenesis by replication in intestinal tuft cells. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span><span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span>&lt;span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; ...
A history of vertebrate RNA viruses
By Vincent Racaniello
Most of the known RNA viruses are from birds and mammals, which represent a small proportion of more recent vertebrate diversity. This omission has been corrected by the discovery of new RNA viruses in hosts that lie across the entire evolutionary history of the vertebrates. Over 186 host species representing ...
Viruses are falling from the skies
By Vincent Racaniello
Viruses with nearly identical genomes are frequently found in diverse environments that are far apart. One possible explanation for this observation is that virus particles are present in the troposphere, where they can be carried long distances on atmospheric flow. To determine how many viruses fall from the troposphere each ...
