A new class is starting at virology blog: Virology 101.
I began this blog in 2004, to give back what I’ve learned from studying viruses for 30+ years. I’ve written many posts on basic virology, but they tend to disappear with time. To remedy this problem, I’ve collected all these posts with links back to the original article, arranged by topic. They are typically short and easy to read; if you start from the top, soon you will have a good basic understanding of virology.
I’ve also included relevant episodes of the podcast TWiV, where we discuss basic virology about once a month.
For the more adventurous, see the video podcasts from my Columbia University virology course, W3310. This course is taught in the spring semester each year. I’ve also included some of my other lectures to medical and undergraduate students.
If you are specifically interested in influenza virus, there is always Influenza 101.
Class will always be in session: there is much more to come.
With this virology course you also get access to a virology professor. If you have any questions, send them to vincent@virology.ws.
Basic Background Information
What is a virus? (W3301)
What is a virus?
Are viruses living?
Discovery of viruses
What color is a virus?
How viruses are classified
Virus classification (TWiV 43)
Simplifying virus classification: The Baltimore system
Viral genomes (TWiV 49)
Genomes and genetics (W3310)
The infectious cycle lecture (W3310)
Measurement (also see the virology toolbox)
Detecting viruses: The plaque assay
How many viruses are needed to form a plaque?
Measurement of viruses by end-point dilution assay
Multiplicity of Infection
The western blot
Detection of antigens or antibodies by ELISA
Detecting viral proteins in infected cells or tissues by immunostaining
Virus Structure
Virus structure (TWiV 39)
Virus structure (W3310)
Attachment and Entry into Cells
Virus entry into cells (TWiV 46)
Attachment and entry (W3310)
Nucleic Acid Synthesis
RNA synthesis (W3310)
Making viral RNA (TWiV 60)
Making viral DNA (TWiV 96)
Making viral DNA II (TWiV 106)
Viral DNA Synthesis (W3310)
Transcription (TWiV 162)
Reverse transcription (W3310)
Reverse transcription (TWiV 66)
Transcription and RNA processing (W3310)
Processing viral RNA (TWiV 216)
Protein synthesis
Translation (W3310)
Virion Assembly
Assembly (W3310)
Pathogenesis and Immunity
Infection Basics (W3310)
Host Defense (W3310)
Virus-Host Interactions (W3310)
Viral Pathogenesis (Medical school lecture)
Acute Infections (W3310)
Antigenic variation explains recurring acute infections
HIV Pathogenesis (W3310)
Transformation and Oncogenesis (W3310)
Innate sensors of DNA
Immunopathology: Too much of a good thing
Innate immune defenses
The inflammatory response
Adaptive immune defenses
Adaptive immune defenses: Antibodies
Virus neutralization by antibodies
The complement system
C1q and the collectins
Natural antibody protects against viral infection
Prevention and Control
Vaccines (W3310)
Antiviral Drugs (W3310)
Tamiflu-resistant pandemic influenza H1N1 virus selected by prophylaxis
Discussion of new HCV antiviral on Futures in Biotech 60
Evolution and Emergence
Viral Evolution (W3310)
Viruses and the tree of life
The abundant and diverse viruses of the seas
Chikungunya: An exotic virus on the move
Lujo virus, a new hemorrhagic fever virus from Southern Africa
The error-prone ways of RNA synthesis
The quasispecies concept
Viral quasispecies and bottlenecks
The number of possible viral variants
Pushing viruses over the error threshold
Increased fidelity reduces viral fitness
Why don’t DNA based organisms discard error repair?
The trajectory of evolution
Virulence: A positive or negative trait for evolution?
Topics that don’t fit anywhere else
Unusual Infectious Agents (W3310)
You write well I really like what you write.
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FAST EFFECTIVE WAY TO GET CURED FROM HERPES VIRUS
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I’m very excited to inform everyone that I’m completely cured from HSV1&2 recently with a strong and active herbal medicine ordered from a powerful herbalist called Dr Balbosa whom my colleague at work introduced me to Dr. BALBOSA completely cured the virus away from my nervous system and I tested negative after 14 days of using the herbal medicine. I’m here to let everyone know that herpes virus has a complete cure and I got rid of it with the help of Dr Balbosa and his herbal exploit. never give up because there is a cure for HERPES 1 & 2…you can contact Dr. BALBOSA from any part of the world on: WHATSAPP/CALL: +1 520-502-9758
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ATTENTION PLEASE!!!
Am so glad to be expressing my profound gratitude to a man that is so concerned about other people’s well being. I was suffering from (HERPES SIMPLEX VIRUS TYPE II) The doctors keep telling me that there is no cure but i believe that there is a cure somewhere and they don’t want people to get cured. I tried searching online if i could see anything that will help me and a comment on YouTube on how Dr Osaro help to cure herpes with herbs and i also saw so many comments about him on many web pages on how he had helped and cured so many people suffering from HERPES 1$2, HPV, CANCER, HIV/AIDS, COLD SORE etc. So I contacted him through his email and I shared my problems with him and he sent me the herbs through UPS and gave me instructions on how to use it. It took me two weeks to finish the herbs and after I finished using it, he told me to go for a medical test, behold the result was negative, now I am HERPES VIRUS free. I just want to use this platform to thank Dr. Osaro for curing me from that horrible disease and also for exposing his herbal cure to the world at large, please you can as well contact Dr Osaro on his email below.
Name: Dr. Osaro Enoma
Email: natureroot.herbs@gmail.com
PHONE/WHATS APP : +(2348077286863}
Dr Osaro herbs is the perfect remedy for Herpes1&2, HPV, HIV and other diseases.
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DR. OSATO`S CURE FOR HERPES1&2 – A NATURAL WAY TO GET HERPES1&2 CURED. If you have been looking for ways to naturally get rid of the herpes simplex virus from your body totally, then you are welcome to read further. Let’s face reality here, you have tried so many counter drugs and you are confused, weak and angry because nothing seems to work. Good News For you my friend…. Yes, I came with good news that will liberate you from the pains and stress of herpes outbreak, you will get total cure from this virus using Dr. Osato Herbal Methodology. Who is Dr. Osato? You may ask. Dr. Osato is a herbalist and a naturalist. He researched and identified some herbs and established a unique methodology to healing the human body using Herbal medicine that was confidently entrenched in his over 30 years of experience. According to him, he has the cure for so many diseases/virus like GENITAL HERPES, HIV, DIABETES, CANCER, HPV, HSV1&2, GENITAL WART, SHINGLES, VAGINAL INFECTION and so many more. You can also contact him through his website: https://osatoherbalcure.wordpress.com I am using this medium to inform everyone how to get treated of herpes using Dr Osato recommended Herbal methodology.
ATTENTION PLEASE!!!
Am so glad to be expressing my profound gratitude to a man that is so concerned about other people’s well being. I was suffering from (HERPES SIMPLEX VIRUS TYPE II) The doctors keep telling me that there is no cure but i believe that there is a cure somewhere and they don’t want people to get cured. I tried searching online if i could see anything that will help me and a comment on YouTube on how Dr Osaro help to cure herpes with herbs and i also saw so many comments about him on many web pages on how he had helped and cured so many people suffering from HERPES 1$2, HPV, CANCER, HIV/AIDS, COLD SORE etc. So I contacted him through his email and I shared my problems with him and he sent me the herbs through UPS and gave me instructions on how to use it. It took me two weeks to finish the herbs and after I finished using it, he told me to go for a medical test, behold the result was negative, now I am HERPES VIRUS free. I just want to use this platform to thank Dr. Osaro for curing me from that horrible disease and also for exposing his herbal cure to the world at large, please you can as well contact Dr Osaro on his email below.
Name: Dr. Enoma Yare
Email: natureroot.herbs@gmail.com
PHONE/WHATS APP : +(2348077286863}
Dr Osaro herbs is the perfect remedy for Herpes1&2, HPV, HIV and other diseases.
I have been suffering from #Herpes disease for the last 2 years without hope for a cure and I was miserable until early this year. I was checking on new developments and cures then I found out how a Great man called doctor Ebose has healed his patients using natural herbal remedies. I Contacted him through his email ebosehealer@gmail.com. He prepare the herbal remedy and sent it to me in LA and after taking the herbal remedy as he instructed i went back to the hospital few weeks later and the test result shows I’m negative and now I’m completely free of genital Herpesthanks to doctor ebose for his urgent response.
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DR. OSATO`S CURE FOR HERPES1&2 – A NATURAL WAY TO GET HERPES1&2 CURED. If you have been looking for ways to naturally get rid of the herpes simplex virus from your body totally, then you are welcome to read further. Let’s face reality here, you have tried so many counter drugs and you are confused, weak and angry because nothing seems to work. Good News For you my friend…. Yes, I came with good news that will liberate you from the pains and stress of herpes outbreak, you will get total cure from this virus using Dr. Osato Herbal Methodology. Who is Dr. Osato? You may ask. Dr. Osato is a herbalist and a naturalist. He researched and identified some herbs and established a unique methodology to healing the human body using Herbal medicine that was confidently entrenched in his over 30 years of experience. According to him, he has the cure for so many diseases/virus like GENITAL HERPES, HIV, DIABETES, CANCER, HPV, HSV1&2, GENITAL WART, SHINGLES, VAGINAL INFECTION and so many more. You can contact him through his website: https://osatoherbalcure.wordpress.com I am using this medium to inform everyone how to get treated of herpes using Dr Osato recommended Herbal methodology.
NATURAL HERBS IS THE REAL DEAL IN CURING HERPES-1&2, HPV, HIV, DAIBETES and CANCER…Contact Dr Osato to get the natural herbs to cure your herpes-1&2. I got the herbs from Dr Osato and I made use of it with the instructions he gave to me on how to use the natural herbal product, after usage I went for a checkup and my result was Negative and all the symptoms of herpes were completely gone from my body. I was cured from herpes-1&2 after using Dr Osato natural herbal medicine. You can contact Dr Osato to get the herbal medicine from him and his website is https://osatoherbalcure.wordpress.com
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