Hosts: Vincent Racaniello, Rich Condit, and Dickson Despommier Vincent, Dickson, and Rich meant to do an all-email episode, but first they review results of the Blood XMRV Scientific Research Working Group, and partial retraction of the paper associating XMRV with chronic fatigue syndrome. With this episode TWiV is three years old. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV150.mp3″] Click the arrow above …
Science Live, the weekly chat at Science magazine, will tackle XMRV and chronic fatigue syndrome on Thursday, 22 September. From the Science Live webpage: Two years ago, Science published a paper suggesting that a mouse retrovirus called XMRV might be involved in chronic fatigue syndrome (CFS), a debilitating disease with no known cause. The study …
The retrovirus XMRV arose during passage of a human prostate tumor in nude mice. The genomes of these mice contain two different proviral DNAs related to XMRV, pre-XMRV-1 and pre-XMRV-2, that recombined to produce XMRV that has been isolated from humans. Two other prostate cancer cell lines also contain mouse gammaretroviruses that are not XMRV. These viruses …
Murine gammaretroviruses in prostate cancer cell lines Read More »
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Stephen Goff Retrovirologist Stephen Goff joins Vincent, Rich, and Alan for a discussion of recent papers on the retrovirus XMRV and its association with chronic fatigue syndrome and prostate cancer. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV136.mp3″] Click the arrow above to play, or right-click to download TWiV #136 (61 MB .mp3, 84 minutes). …
The novel human retrovirus XMRV has been associated with prostate cancer and chronic fatigue syndrome. The nucleotide sequence of XMRV isolated from humans indicates that the virus is nearly identical with XMRV produced from a human prostate tumor cell line called 22Rv1. This cell line was derived by passage of human prostate tumor tissue in …
Late last year virologist Ian Lipkin was asked by National Institute of Allergy and Infectious Diseases head Anthony Fauci to coordinate a multi-center study of CFS patients. Newly drawn blood samples from 100 CFS patients and 100 healthy controls from around the US will be blinded and sent to three groups – FDA, CDC and the …
