Bacteriophages are the most abundant biological entities on Earth. There are 1031 of them on the planet, and they infect 1023 to 1025 bacteria every second. That’s a lot of lysis, and it leads to the release of huge quantities of DNA that can be taken up by other organisms, leading to new traits. It …
At the Rocky Mountain Laboratory in Hamilton, Montana, Vincent speaks with Vincent Munster about the work of his laboratory on MERS-coronavirus and Ebolaviruses. You can find this TWiV Special at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiVspecialmunster.mp3″] Click arrow to play Download TWiV Special (34 MB .mp3, 56 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!
The TWiVoids discuss the March for Science, the GOF moratorium, and a classic virology paper on mapping the gene order for vesicular stomatitis virus. You can find TWiV #427 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV427.mp3″] Click arrow to play Download TWiV 427 (59 MB .mp3, 98 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!
The sages of TWiV explain how chronic wasting disease of cervids could be caused by spontaneous misfolding of prion protein, and the role of the membrane protein Axl in Zika virus entry into cells. You can find TWiV #426 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV426.mp3″] Click arrow to play Download TWiV 426 (66 MB .mp3, 110 min) Subscribe …
TWiV 426: I’m Axl, and I’ll be your cervid today Read More »
The TWiVaniellos discuss a thermostable poliovirus empty capsid vaccine, and two cell genes that act as a switch between entry and clearance of picornavirus infection. You can find TWiV #425 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV425.mp3″] Click arrow to play Download TWiV 425 (65 MB .mp3, 107 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!
A unique feature of eukaryotic cells, which distinguishes them from bacteria, is the presence of a membrane-bound nucleus that contains the chromosomal DNA (illustrated; image credit). Surprisingly, a nucleus-like structure that forms during viral infection of bacteria is the site of viral DNA replication (link to paper). During infection of Pseudomonas bacteria with the phage 2O1phi2-1, a …
