viruses

TWiV 469: Mycovirus stuffed potatoes

2 Comments / This Week in Virology / By Vincent Racaniello

The TWiV hosts discuss a plant virus that infects a fungus, and whether you need to work insane hours to succeed in science. Click arrow to play Download TWiV 469 (66 MB .mp3, 108 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

TWiV 468: Zika by the slice

2 Comments / This Week in Virology / By Vincent Racaniello

Amy Rosenfeld joins the TWiV team to talk about her career and her work on Zika virus neurotropism using embryonic mouse organotypic brain slice cultures. Click arrow to play Download TWiV 468 (66 MB .mp3, 107 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

Lymphocytes after dark

2 Comments / Basic virology, Information / By Vincent Racaniello

When you are infected with a microbe, pieces of the pathogen are picked up by sentinel dendritic cells and brought to local lymph nodes. There the sentinels present their gifts to lymphocytes – B (pictured; image credit) and T cells – who then decide if they are foreign, in which case an immune response begins. …

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Zika virus blocks the neuron road

4 Comments / Basic virology, Information / By Vincent Racaniello

Written with Amy Rosenfeld, Ph.D. By infecting organotypic brain slice cultures from embryonic mice, we have shown that Zika virus has always been neurotropic. The same culture system provides information on how Zika virus infection of the developing brain might lead to microcephaly.

TWiV 466: The Capsid Club

1 Comment / This Week in Virology / By Vincent Racaniello

From Indiana University, Vincent and Kathy speak with Tuli Mukhopadhyay, John Patton, and Adam Zlotnick about their careers and their work on alphaviruses, hepatitis B virus, and rotaviruses. Click arrow to play Download TWiV 466 (40 MB .mp3, 66 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

TWiV 465: Theodora the explorer

1 Comment / This Week in Virology / By Vincent Racaniello

Theodora Hatziioannou joins the TWiV team to discuss a macaque model for AIDS, and how a cell protein that blocks HIV-1 infection interacts with double-stranded RNA. Click arrow to play Download TWiV 465 (53 MB .mp3, 88 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

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