Mice are important animal models for studying human pathogens, but they have limitations: not all human viruses replicate in mice and often these animals do not reproduce aspects of disease and immune responses. Mice implanted with human bone marrow, liver, and thymus (BLT mice) develop human immune systems, but most pathogens infect other cell types. …
TWiV travels to Rutgers University to speak with Brad, Kay, Siobain, and Kim about their careers and their work on viruses of plants, fungi, bacteria, diatoms, and coccolithophores. Click arrow to play Download TWiV 562 (77 MB .mp3, 127 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
In the 19th century the word ‘virus€™ was used to describe the cause of any contagious disease. How it came to describe the very small intracellular parasites that we know today is a fascinating story that illustrates our evolving concepts of infectious agents. Long before bacteria, fungi, and viruses were identified, it was known that …
The Autonomous CollecTWiVe reveal two effective treatments for Ebolavirus infection, how a virus in a fungus confers heat tolerance to a plant, and dampened inflammation as a mechanism for bat tolerance to viral infection. Click arrow to play Download TWiV 561 (57 MB .mp3, 93 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
The Centers for Disease Control and Prevention thinks that viruses play a role in the childhood paralysis called acute flaccid myelitis (AFM). The finding of antibodies to enterovirus D68 (EV-D68) in the cerebrospinal fluid of patients with AFM strengthens the link between infection with this virus and AFM. Acute flaccid myelitis (AFM), which mainly occurs …
From the meeting of the Centers of Excellence for Influenza Research and Surveillance, Vincent speaks with Alan, Florian and Jennifer about their careers, the purpose of CEIRS, universal influenza vaccines, and cellular responses to infection in pediatric populations. Click arrow to play Download TWiV 560 (37 MB .mp3, 61 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes …
