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How influenza virus inhibits early antiviral responses

The fact that viruses routinely and frequently cause disease shows that our defense mechanisms are imperfect. This occurs in large part because nearly every viral genome encodes one or more countermeasures to modulate host defenses. Influenza virus is no exception. One of the viral proteins, called NS1, is particularly adept at impairing the synthesis of …

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Pathogenesis of influenza in humans

When influenza virus is introduced into the respiratory tract, by aerosol or by contact with saliva or other respiratory secretions from an infected individual, it attaches to and replicates in epithelial cells. The virus replicates in cells of both the upper and lower respiratory tract. Viral replication combined with the immune response to infection (which …

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Futures in Biotech 43: Temporal Alien Mammoth Overlords

I joined host Marc Pelletier and Andre Nantel, Justin Sanchez, and Dave Brodbeck for a discussion on recent big stories in bioscience. Topics included wooly mammoths, cybernetics, viruses in the oceans, and controlling your computer with your brain. Download Futures in Biotech 43 or subscribe to the podcast in iTunes.

TWiV 34: Arsenic and facemasks

On episode 34 of the podcast “This Week in Virology”, Vincent, Alan, and Stephen Morse discuss progressive vaccinia in a smallpox vaccinee, arsenic and influenza in mice, facemasks and flu transmission, and antigenic and genetic analyses of the new H1N1 influenza virus. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV034.mp3″] Click the arrow above to play, or right-click to download TWiV …

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