virus

Was the swine influenza threat underestimated?

Many virologists, including myself, believe that the threat of avian H5N1 influenza is not only overestimated, but also distracts from serious consideration of other potential pandemic strains. In early 2005 I wrote about this problem (“Should we worry about avian influenza?) and suggested that we should pay attention to H2N2 strains as a potential pandemic …

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TWiV 35: Much achoo about nothing

In episode 35 of the podcast “This Week in Virology”, Vincent, Alan, Dick, and Richard Kessin talk about Lujo virus, a new arenavirus, influenza, WHO rewriting pandemic rules, adjuvants, and a brief history of microbiology. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV035.mp3″] Click the arrow above to play, or right-click to download TWiV #35 or subscribe in iTunes or by …

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Interferons and secondary pneumonia after influenza

Now that we have discussed influenza pathogenesis in humans and the innate immune defenses, we can tackle the conclusion that type I IFN mediates the development of secondary bacterial pneumonia in mice. Secondary bacterial pneumonia occurs after the patient has begun to recover from influenza infection, and often influenza virus can no longer be isolated. …

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