virus

PMRV joins XMRV as possible etiologic agent of chronic fatigue syndrome

The new human retrovirus XMRV, first detected in malignant prostate tissue, was subsequently identified in a high percentage of patients with chronic fatigue syndrome (CFS). The virus was not detected in four independent studies of CFS patients in Europe or the United States. The results of a second American study, whose publication was blocked for …

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Viral bioinformatics: Recombination

This week€™s addition to the virology toolbox was written by Danielle Coulson and Chris Upton Comparing genomes of viral strains can provide very useful insight into evolutionary relationships. Recombination, defined by Posada et al (2001) as the exchange of genetic information between two nucleotide sequences, is quite common in many viruses. Because recombination accounts for …

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TWiV 97: California virology

Hosts: Vincent Racaniello, Peter Sarnow, and Bert Semler On episode #97 of the podcast This Week in Virology, Vincent visited Peter Sarnow and Bert Semler during a trip to California, and spoke with them about their work on internal ribosome entry, and the requirement for a cellular microRNA for hepatitis C virus replication. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV097.mp3″] Click …

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TWiV 96: Making viral DNA

Hosts: Vincent Racaniello, Dickson Despommier, and Rich Condit On episode #96 of the podcast This Week in Virology, Vincent, Dickson, and Rich continue Virology 101 with a discussion of how viruses with DNA genomes replicate their genetic information. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV096.mp3″] Click the arrow above to play, or right-click to download TWiV #96 (65 MB .mp3, 90 minutes) …

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TWiV 95: Does a virus shift in the woods?

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit On episode #95 of the podcast This Week in Virology, Vincent, Dickson, Alan, and Rich consider the end of the influenza H1N1 pandemic, dengue in Florida, vaccinia virus infection in Brazilian monkeys, and viruses in the faecal microbiota. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV095.mp3″] Click the arrow above to play, or …

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XMRV not detected in seminal plasma

How XMRV, the new human retrovirus associated with prostate cancer and chronic fatigue syndrome, might be transmitted among humans is unknown. The finding that the virus can be detected in prostate cancer cells, and in prostatic secretions of men with prostate cancer suggests that it could be sexually transmitted. To address this question, the presence …

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