Analysis of poliovirus recovered from the stool of a patient with fatal poliomyelitis revealed that she had been infected with the virus 12 years earlier, probably when one of her children received the oral poliovirus vaccine. This case has the longest known incubation period for vaccine-derived poliomyelitis, and highlights our still rudimentary understanding of how …
Poliomyelitis after a twelve year incubation period Read More »
Hosts: Vincent Racaniello, Alan Dove, and Dickson Despommier Vincent, Alan, and Dickson discuss the reduction in genome size of Mimivirus upon passage in amoeba, and analysis of the microbiome of honeybees. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV139.mp3″] Click the arrow above to play, or right-click to download TWiV #139 (96 MB .mp3, 80 minutes). Subscribe to TWiV (free) in …
The retrovirus XMRV arose during passage of a human prostate tumor in nude mice. The genomes of these mice contain two different proviral DNAs related to XMRV, pre-XMRV-1 and pre-XMRV-2, that recombined to produce XMRV that has been isolated from humans. Two other prostate cancer cell lines also contain mouse gammaretroviruses that are not XMRV. These viruses …
Murine gammaretroviruses in prostate cancer cell lines Read More »
Hosts: Vincent Racaniello and Raul Andino Vincent meets up with Raul Andino in San Francisco to discuss the RNAi-based antiviral defense system of Drosophila, the fruit fly, and how it is antagonized by viruses. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV138.mp3″] Click the arrow above to play, or right-click to download TWiV #138 (53 MB .mp3, 73 minutes). Subscribe to TWiV …
Visualization of M13 virus (orange strand to the right) using the surface proteins (purple strands) to grab the carbon nanotubes and put them in order. Image credit: Matt Klug, Biomolecular Materials Group, MIT. This article was written for extra credit by a student in my recently concluded virology course. by Ian Blubaugh A team at MIT …
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Dickson Despommier, Amit Kapoor, and Ian Lipkin The TWiV team speaks with Amit Kapoor and Ian Lipkin about how they discovered canine hepacivirus, and its implications for the origin and evolution of hepatitis C virus. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV137.mp3″] Click the arrow above to play, or right-click to download TWiV #137 …
