virus

TWiV 263: Game of clones

On episode #263 of the science show This Week in Virology, Ben tenOever joins the TWiV team to reveal the winner of his contest in which influenza viruses carrying different interferon-stimulated genes vie against one another in mice. You can find TWiV #263 at www.microbe.tv/twiv.

TWiV 261: Giants among viruses

On episode #261 of the science show This Week in Virology, Vincent meets up with Chantal and Jean-Michel at the first International Symposium on Giant Virus Biology in Tegernsee, Germany, to discuss their work on Mimivirus, Megavirus, and Pandoravirus. You can find TWiV #261 at www.microbe.tv/twiv.

TWiV 260: Badgers go viral

On episode #260 of the science show This Week in Virology, Vincent visits the University of Wisconsin, Madison and speaks with Tom, Tony, and David about their work on virus discovery at the AIDS Vaccine Research Laboratory. You can find TWiV #260 at www.microbe.tv/twiv.

Changing influenza virus neuraminidase into a receptor binding protein

The hemagglutinin (HA) and neuraminidase (NA) glycoproteins of the influenza virus particle serve distinct functions during infection. The HA binds sialic acid-containing cellular receptors and mediates fusion of the viral and cell membranes, while the NA removes sialic acids from glycoproteins. Apparently this division of labor is not absolute: influenza viruses have been identified with …

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