virology

TWiV 414: Zika in the guys with Diamond

On episode #414 of the science show This Week in Virology, Michael Diamond visits the TWiV studio to talk about chikungunya virus and his laboratory’s work on a mouse model of Zika virus, including the recent finding of testicular damage caused by viral replication. You can find TWiV #414 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV414.mp3″] Click arrow …

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TWiV 413: Partnerships not parachutes

From the EIDA2Z conference at Boston University, Vincent, Alan and Paul meet up with Ralph Baric, Felix Drexler, Marion Koopmans, and Stacey Schultz-Cherry to talk about discovering, understanding, protecting, and collaborating on emerging infectious diseases. You can find TWiV #413 at microbe.tv/twiv, or watch or listen here. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV413.mp3″] Click arrow to play Download TWiV 413 (44 MB …

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Genome recombination across viral families

 A novel coronavirus isolated from bats in China is unusual because the genome contains a gene from a virus in a completely different family, the Reoviridae (link to paper). The finding suggests that recombination occurred between a (+) strand RNA virus and a virus with a segmented, double-stranded RNA genome. The unusual recombinant virus was identified …

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TWiV 412: WO, open the borders and rig the infection

The TWiVome reveal the first eukaryotic genes found in a bacteriophage of Wolbachia, and how DNA tumor virus oncogenes antagonize sensing of cytoplasmic DNA by the cell. You can find TWiV #412 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV412.mp3″] Click arrow to play Download TWiV 412 (73 MB .mp3, 121 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!

A new function for oncoproteins of DNA tumor viruses

Oncogenes of DNA tumor viruses encode proteins that cause cells to divide incessantly, eventually leading to formation of a tumor. These oncoproteins have now been found to antagonize the innate immune response of the cell (link to paper). Most cells encountered by viruses are not dividing, and hence do not efficiently support viral DNA synthesis. The …

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TWiV 411: Chicken runs

The TWiVeroos examine a reverse spillover of Newcastle disease virus vaccines into wild birds, and identification of a protein cell receptor for murine noroviruses. You can find TWiV #411 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV411.mp3″] Click arrow to play Download TWiV 411 (59 MB .mp3, 95 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!

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