Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Alan Rein On episode #113 of the podcast This Week in Virology, Vincent, Alan, and Rich discuss the retrovirus XMRV with retrovirologist Alan Rein of the National Cancer Institute. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV113.mp3″] Click the arrow above to play, or right-click to download TWiV #113 (55 MB .mp3, 76 minutes). Subscribe to …
Yesterday the Chicago Tribune published my reaction to the four papers on the retrovirus XMRV published this week in the journal Retrovirology. I was quoted as saying “These four papers are probably the beginning of the end of XMRV and CFS”. I wish to retract this statement and explain my reasons for doing so. Early Monday a …
Since the first observations that the human retrovirus XMRV is associated with prostate cancer and chronic fatigue syndrome (CFS), new studies have been carried out to determine the role of the virus in these diseases. The results have been conflicting: XMRV (and related retroviruses) have been found in some patients, but not in others. Whether laboratory contamination …
Hosts: Vincent Racaniello, Alan Dove, and Rich Condit On episode #112 of the podcast This Week in Virology, Vincent, Alan, and Rich review the making of a virulent poxvirus by insertion of the gene encoding IL-4, and severe 2009 H1N1 influenza due to pathogenic immune complexes. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV112.mp3″] Click the arrow above to play, or right-click to …
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Ed Fussell, Andrea Leal, and Amy Sargent On episode #111 of the podcast This Week in Virology, the TWiV crew meets with members of the Florida Keys Mosquito Control District at Florida Gulf Coast University to discuss dengue in Florida and how to control it. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV111.mp3″] Click the arrow …
During the replication of retroviruses, a double-stranded DNA copy of the viral RNA genome is synthesized by reverse transcription and integrated into the genomes of the infected cell. When retroviral DNA is integrated into the DNA of germ line cells, it is passed on to future generations in Mendelian fashion as an endogenous provirus. Until …
