virology

TWiV 139: Honey, I shrunk the virus

Hosts: Vincent Racaniello, Alan Dove, and Dickson Despommier Vincent, Alan, and Dickson discuss the reduction in genome size of Mimivirus upon passage in amoeba, and analysis of the microbiome of honeybees. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV139.mp3″] Click the arrow above to play, or right-click to download TWiV #139 (96 MB .mp3, 80 minutes). Subscribe to TWiV (free) in …

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Murine gammaretroviruses in prostate cancer cell lines

The retrovirus XMRV arose during passage of a human prostate tumor in nude mice. The genomes of these mice contain two different proviral DNAs related to XMRV, pre-XMRV-1 and pre-XMRV-2, that recombined to produce XMRV that has been isolated from humans. Two other prostate cancer cell lines also contain mouse gammaretroviruses that are not XMRV. These viruses …

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TWiV 138: RISCy business with Raul Andino

Hosts: Vincent Racaniello and Raul Andino Vincent meets up with Raul Andino in San Francisco to discuss the RNAi-based antiviral defense system of Drosophila, the fruit fly, and how it is antagonized by viruses. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV138.mp3″] Click the arrow above to play, or right-click to download TWiV #138 (53 MB .mp3, 73 minutes). Subscribe to TWiV …

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Viruses go green

Visualization of M13 virus (orange strand to the right) using the surface proteins (purple strands) to grab the carbon nanotubes and put them in order. Image credit: Matt Klug, Biomolecular Materials Group, MIT. This article was written for extra credit by a student in my recently concluded virology course. by Ian Blubaugh A team at MIT …

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TWiV 137: Look what the dog dragged in

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Dickson Despommier, Amit Kapoor, and Ian Lipkin The TWiV team speaks with Amit Kapoor and Ian Lipkin about how they discovered canine hepacivirus, and its implications for the origin and evolution of hepatitis C virus. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV137.mp3″] Click the arrow above to play, or right-click to download TWiV #137 …

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TWiV 136: Exit XMRV

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Stephen Goff Retrovirologist Stephen Goff joins Vincent, Rich, and Alan for a discussion of recent papers on the retrovirus XMRV and its association with chronic fatigue syndrome and prostate cancer. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV136.mp3″] Click the arrow above to play, or right-click to download TWiV #136 (61 MB .mp3, 84 minutes). …

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