Health and Human Services (HHS) Secretary Kathleen Sebelius announced on Friday that she is allocating $1 billion in existing funds to purchase large quantities of vaccine against the novel H1N1 influenza strain, and to conduct clinical trials this summer to determine if an adjuvant can be used. If this money is being taken away from …
US to redirect $1 billion to study adjuvant for influenza vaccine Read More »
Episode 33 of the podcast “This Week in Virology” was recorded before an audience at the ASM General Meeting in Philadelphia. Vincent, Alan, Dick, and Raul Andino discussed increased arterial blood pressure caused by cytomegalovirus infection, restriction of influenza replication at low temperature by the avian viral glycoproteins, first isolation of West Nile virus in …
Does previous exposure to influenza H1N1 viruses, either by infection or vaccination, provide any protection against infection with the new H1N1 influenza virus strains? The answer to this question might provide insight as to why over 60% of confirmed cases of influenza caused by the swine-like H1N1 viruses in the US are in 5- to …
Adults have cross-reactive antibodies to A/California/04/2009 (H1N1) Read More »
Now that we have a rudimentary understanding of influenza virus replication, we can begin to consider how the virus causes disease – a field of study called viral pathogenesis. The first step in this process is virus entry into the body. The human body is covered with skin, which has a dead outer layer that …
The recent series of posts on polymerase error rates and viral evolution has elicited many excellent and thought provoking comments from readers of virology blog. Here is one that I had not thought of before, and which I’ll use on an exam in my virology course: Here’s a tough question. In the follow up blog …
Why don’t DNA based organisms discard error repair? Read More »
Our discussion of influenza virus replication has so far brought us to the stage of viral RNA synthesis. Last time we discussed the formation of viral RNAs, an event which takes place in the cell nucleus. Now we’ll consider how these RNAs participate in the assembly of new infectious viral particles, as illustrated in the …
