viral

Pathogenesis of influenza in humans

When influenza virus is introduced into the respiratory tract, by aerosol or by contact with saliva or other respiratory secretions from an infected individual, it attaches to and replicates in epithelial cells. The virus replicates in cells of both the upper and lower respiratory tract. Viral replication combined with the immune response to infection (which …

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Futures in Biotech 43: Temporal Alien Mammoth Overlords

I joined host Marc Pelletier and Andre Nantel, Justin Sanchez, and Dave Brodbeck for a discussion on recent big stories in bioscience. Topics included wooly mammoths, cybernetics, viruses in the oceans, and controlling your computer with your brain. Download Futures in Biotech 43 or subscribe to the podcast in iTunes.

TWiV 34: Arsenic and facemasks

On episode 34 of the podcast “This Week in Virology”, Vincent, Alan, and Stephen Morse discuss progressive vaccinia in a smallpox vaccinee, arsenic and influenza in mice, facemasks and flu transmission, and antigenic and genetic analyses of the new H1N1 influenza virus. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV034.mp3″] Click the arrow above to play, or right-click to download TWiV …

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Lujo virus, a new hemorrhagic fever virus from Southern Africa

A new member of the arenavirus family, Lujo virus, has been identified in patients who died during an outbreak of hemorrhagic fever in late 2008. Sequence analysis reveals that Lujo is a new arenavirus, genetically distinct from other members of the family which includes Lassa virus. A patient with unexplained hemorrhagic fever was identified in …

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Influenza hemagglutination inhibition assay

Centers for Disease Control and Prevention have determined that some adults have serum cross-reactive antibodies to the new influenza H1N1 virus. One of the techniques used to reach this conclusion is the hemagglutination inhibition (HI) assay. How does this assay work? To understand the HI assay, we must discuss the hemagglutination assay. Influenza virus particles …

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