Virology lecture #17: Acute infections
Download: .wmv (322 MB) | .mp4 (91 MB) Visit the virology W3310 home page for a complete list of course resources.
viral
TWiV #78: Darwin gets weird
Hosts: Vincent Racaniello, Alan Dove, Dickson Despommier, and Rich Condit Vincent, Alan, Dickson, and Rich talk about treating arthritis with a tanapox virus protein, Darwinian evolution of prions in cell culture, and the connection between cold weather fronts and outbreaks of avian H5N1 influenza in Europe. This episode is sponsored by Data Robotics Inc. Use …
Virology lecture #16: Persistent infections
Download: .wmv (331 MB) | .mp4 (68 MB) Presented by guest lecturer Saul Silverstein, Ph.D. Visit the virology W3310 home page for a complete list of course resources.
Poliovirus vaccine, SV40, and human cancer
Deep sequencing – which identified a viral contaminant of the rotavirus vaccine Rotarix – could have revealed the presence of simian virus 40 (SV40) in the poliovirus vaccine, had the technique been available in the 1950s. Exposure of over 100 million Americans to SV40, and many more worldwide, could have been avoided, as well as the debate …
TWiV 77: Non-nuclear proliferation
Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich revisit circovirus contamination of Rotarix, then discuss poxvirus-like replication of mimivirus in the cell cytoplasm, and whether seasonal influenza immunization increases the risk of infection with the 2009 H1N1 pandemic virus. This episode is sponsored by Data Robotics Inc. Use the promotion code …
Poliovirus vaccine safety
The contamination of the rotavirus vaccine Rotarix with porcine circovirus 1 DNA was revealed by deep sequencing. The same technique was also used to demonstrate that oral poliovirus vaccine does not contain viruses that can cause poliomyelitis. The oral poliovirus vaccine strains developed by Albert Sabin (pictured) were licensed in the United States in 1962, …