vector

An ancestral vector improves on this year€™s model

Adenovirus associated virus (AAV) vectors are being increasingly used for gene therapy because they are not pathogenic in humans and persist for long periods in certain cell types. Currently 120 gene delivery clinical trials with these vectors are in progress, and two have been approved: Luxturna to treat a rare form of blindness, and another …

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CRISPR-ing HIV-1

By Gertrud U. Rey Although antiretroviral therapy (ART) has been highly effective at controlling HIV-1 viral loads in the bloodstream of infected individuals, the virus remains latent in infected cells and starts replicating within a couple of weeks upon termination of therapy.

TWiV 508: Bioweapon

Jens Kuhn returns to present a brief history of bioweapons, with a focus on the program in the Soviet Union, the largest ever undertaken, and his experience working in the decommissioned Soviet bioweapons laboratory known as Vector. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; …

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TWiV 422: Watching the icosahedron drop

The TWiVestigators wrap up 2016 with a discussion of the year’s ten compelling virology stories. You can find TWiV #422 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV422.mp3″] Click arrow to play Download TWiV 422 (71 MB .mp3, 117 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!

TWiV 395: The cancer thief

Vincent, Rich and Kathy speak with Stephen Russell about his career and his work on oncolytic virotherapy €“ using viruses to treat cancers. Recorded before an audience at ASV 2016 at Virginia Tech in Blacksburg, Virginia. You can find TWiV #395 at microbe.tv/twiv, or listen/view below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV395.mp3″] Click arrow to play Download TWiV 395 (44 MB .mp3, 60 min) Subscribe (free): iTunes, RSS, email, Google Play Music Become …

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