vaccine

TWiV 420: Orthogonal vectors

The TWiV gurus describe how to use an orthogonal translation system to produce infectious but replication-incompetent influenza vaccines. You can find TWiV #420 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV420.mp3″] Click arrow to play Download TWiV 420 (70 MB .mp3, 116 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!

TWiV Special: Gary Nabel on World AIDS Day 2016

For World AIDS Day 2016, Vincent speaks with Gary Nabel, Chief Scientific Officer at Sanofi and former Director of the Vaccine Research Institute of NIAID, about his career and his work on HIV vaccines. You can find this TWiV Special at microbe.tv/twiv, or listen and watch here. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV-special-nabel.mp3″] Click arrow to play Download this TWiV Special (25 MB …

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TWiV 413: Partnerships not parachutes

From the EIDA2Z conference at Boston University, Vincent, Alan and Paul meet up with Ralph Baric, Felix Drexler, Marion Koopmans, and Stacey Schultz-Cherry to talk about discovering, understanding, protecting, and collaborating on emerging infectious diseases. You can find TWiV #413 at microbe.tv/twiv, or watch or listen here. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV413.mp3″] Click arrow to play Download TWiV 413 (44 MB …

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TWiV 403: It’s not easy being vaccine

The TWiV team takes on an experimental plant-based poliovirus vaccine, contradictory findings on the efficacy of Flumist, waning protection conferred by Zostavax, and a new adjuvanted subunit zoster vaccine. You can find TWiV #403 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV403.mp3″] Click arrow to play Download TWiV 403 (70 MB .mp3, 96 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!

Whole plant cells producing viral capsid protein as a poliovirus vaccine candidate

Although the use of the live, attenuated (Sabin) poliovirus vaccines has been instrumental in nearly eradicating the virus from the planet, the rare reversion to virulence of these strains has lead to the World Health Organization to recommend their replacement with inactivated poliovirus vaccine (IPV). Unfortunately IPV is also not without shortcomings, including high cost, failure …

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