What does the future hold for SARS-CoV-2? Will it remain in its current configuration, with 20% of infections causing serious damage? Will everyone on Earth need to be vaccinated regularly to prevent infection? Allow me to indulge in some speculation and suggest that SARS-CoV-2 will eventually become the fifth common cold coronavirus (CoV). There are …
Daniel Griffin provides a clinical report on COVID-19, then former FDA Chief of Staff to the Commissioner Denise Esposito joins us to explain the challenges in approving vaccines, antiviral drugs, and diagnostic tests during a pandemic, followed by answers to listener questions. Click arrow to playDownload TWiV 651 (98 MB .mp3, 164 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become …
Daniel Griffin provides a clinical report on COVID-19, followed by a review of the findings that children shed as much SARS-CoV-2 viral RNA from the respiratory tract as older patients, the lineage giving rise to SARS-CoV-2 has been circulating in bats in China for decades, and answers to listener questions. Click arrow to playDownload TWiV 648 …
by Gertrud U. Rey On July 20, 2020, Oxford University’s Jenner Institute and the pharmaceutical company AstraZeneca reported preliminary results from phase I/II clinical trials assessing the safety and efficacy of a vaccine candidate against SARS-CoV-2. The vaccine candidate, named AZD1222 (referred to in the publication as ChAdOx1 nCoV-19), consists of an adenovirus vector with an …
Preliminary phase I/II results of ChAdOx1 SARS-CoV-2 vaccine Read More »
by Gertrud Rey In a highly publicized press release dated May 18, 2020, the biotech company Moderna announced preliminary results from a phase I clinical trial for a SARS-CoV-2 vaccine candidate. However, the company only provided brief, conclusory statements at that time. On July 14, the results from the trial were finally published in the New …
In this episode, approval of an Ad5 vectored SARS-CoV-2 vaccine for the military in China, description and clinical trials of a Novavax vaccine joining Operation Warp Speed, prevalence of SARS-CoV-2 in Spain, shedding and transmissibility of the virus, and listener email. Click arrow to playDownload TWiV 637 (66 MB .mp3, 109 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! …
