vaccine

TWiV 831: COVID-19 clinical update #89 with Dr. Daniel Griffin

This Week in Virology / By Vincent Racaniello

In COVID-19 clinical update #89, Dr. Griffin reviews upcoming meeting on FDA emergency use authorization for molnupiravir, 25% of US cases in children, reinfection associates with presence of antibodies, national surveillance for acute flaccid myelitis in the US, and monoclonal antibody treatment of infection in vaccinated, high-risk individuals. Click arrow to playDownload TWiV 831 (20 MB .mp3, …

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TWiV 828: COVID-19 clinical update #88 with Dr. Daniel Griffin

This Week in Virology / By Vincent Racaniello

In COVID-19 clinical update #88, Dr. Griffin covers vaccine protection among US veterans, absence of long COVID in vaccinated who are infected, single dose of REGEN-COV monoclonal antibody cocktail provides long term protection, and Pfizer protease inhibitor Paxlovid is 89% effective in preventing hospitalization or death. Show notes at microbe.tv/twiv

Spikevax Induces Durable Protection from the Delta Variant in Rhesus Macaques

Rhesus macaques that are vaccinated against SARS-CoV-2 are protected from severe disease and probably transmit very little virus when infected with SARS-CoV-2 one year later.

T cells will save us from COVID-19, part 3

10 Comments / Basic virology / By Vincent Racaniello

In the two previous installments (one, two) of what has now become my praise of T cells, I explained that the SARS-CoV-2 protein sequences recognized by T cells do not change, likely explaining why vaccines prevent serious disease and death caused by any variant. Today I will explain that virus-specific T cells appear a week …

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Dynamics of SARS-CoV-2 Vaccine-Induced Antibody Immunity

2 Comments / Basic virology, Gertrud Rey / By Gertrud U. Rey

It is slowly becoming clear that the immunity induced by SARS-CoV-2 vaccination is of overall better quality than that induced by COVID-19.

T cells will save us from COVID-19, part two

8 Comments / Basic virology, Information / By Vincent Racaniello

T cells are the other arm of the adaptive immune response (in addition to B cells) that are essential for clearing virus infections. Most studies of immunity to SARS-CoV-2 infection have focused on antibodies and their ability to neutralize virus infection. The observation that variants of concern are less effectively neutralized by antibodies against ancestral …

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